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Treatment of Recurrent or Refractory Chronic Lymphocytic Leukemia
For information about the treatments listed below, see the Treatment Option Overview section.
The treatment of recurrent or refractory chronic lymphocytic leukemia (CLL) may include therapies and clinical trials.
- Targeted therapy with any of the following drugs:
- A tyrosine kinase inhibitor (acalabrutinib, zanubrutinib, or ibrutinib).
- Venetoclax with or without obinutuzumab or rituximab.
- Ofatumumab with or without chemotherapy.
- Duvelisib.
- Chemotherapy with or without rituximab.
- Immunotherapy (lenalidomide) with or without rituximab.
- Bone marrow or peripheral blood stem cell transplantation.
- Radiation therapy as palliative treatment to relieve symptoms and improve quality of life.
- A clinical trial of CAR T-cell therapy.
This information is not intended to replace the advice of a doctor.
Navigating Care disclaims any liability for the decisions you make based on this information.
This information was sourced and adapted from Adapted from the National Cancer Institute's
Physician Data Query (PDQ®) Cancer Information Summaries on
www.cancer.gov.
This information updated
December 1, 2024.
Learn more:
- General Information About Chronic Lymphocytic Leukemia
- Stage Information for Chronic Lymphocytic Leukemia
- Treatment Option Overview
- Treatment of Asymptomatic Chronic Lymphocytic Leukemia
- Treatment of Symptomatic or Progressive Chronic Lymphocytic Leukemia
- Treatment of Recurrent or Refractory Chronic Lymphocytic Leukemia
- To Learn More About Chronic Lymphocytic Leukemia
Related Articles
- General Information About Chronic Lymphocytic Leukemia
- Stage Information for Chronic Lymphocytic Leukemia
- Treatment Option Overview
- Treatment of Asymptomatic Chronic Lymphocytic Leukemia
- Treatment of Symptomatic or Progressive Chronic Lymphocytic Leukemia
- Treatment of Recurrent or Refractory Chronic Lymphocytic Leukemia
- To Learn More About Chronic Lymphocytic Leukemia
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